Molecular basis for recruitment of STIM1 to the CRAC channels Orai1 and Orai3

来源 :The 10th Chinese Symposium on Calcium Signaling(第十届全国钙信号和细胞功 | 被引量 : 0次 | 上传用户:ewtfgtwegv
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Store-operated calcium entry (SOCE) is critical for T cell activation and numerous calcium related processes.The activation of SOCE requires engagement between stromal interaction molecule 1 (STIMI) molecules on the endoplasmic reticulum and Ca2+ release-activated Ca2+ (CRAC) channels Orai on the plasma membrane.
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