Cyanines covering the absorption in the near infrared(NIR)are attractive for distinct applications.They can interact either with lasers exhibiting line-shaped focus emitting at both 808 nm and 980 nm or bright high intensity NIR-LEDs with 805 nm emission,respectively.This has and is drawing attention to Industry 4.0 applications.The major deactivation occurs non-radiative resulting in the release of heat into the surrounding though small fraction of radiative deactivation also occurs.Most of these NIR-sensitive systems possess an internal activation barrier to react in a photonic process with initiators resulting in generation of reactive radicals and acidic cations.Molecular design strategies make these systems more compatible with distinct applications in a certain oleophilic surrounding.Further discussion focusses on the use of such systems in Chemistry 4.0 related applications.Intelligent software tools help to improve and optimize these systems combining chemistry,engineering based HTFS technologies,and machine learning algorithms to open up novel solutions in material sciences.Up-conversion nanoparticles facilitating laser excitation at 980 nm resulting in generation of blue light and UV light complement these patterns.