Substructure-activity relationship studies on antibody recognition for phenylurea compounds using co

来源 :第九届国际分子模拟与信息技术应用学术会议(ICMS&I2018) | 被引量 : 0次 | 上传用户：xtcwang

【摘要】

：

Based on the structural features of fluometuron,an immunizing hapten was synthesized and conjugated to bovine serum albumin as an immunogen to prepare a polyclo

【作者】

：

Fuyuan Zhang Bing Liu Guozhen Liu Yan Zhang Junping Wang Shuo Wang

【机构】

：

KeyLaboratoryofFoodNutritionandSafety,MinistryofEducationofChina,TianjinUniversityofScienceandTechno

【出处】

：

第九届国际分子模拟与信息技术应用学术会议(ICMS&I2018)

【发表日期】

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2018年5期

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Based on the structural features of fluometuron,an immunizing hapten was synthesized and conjugated to bovine serum albumin as an immunogen to prepare a polyclonal antibody.However,the resultant antibody indicated cross-reactivity with 6 structurally similar phenylurea herbicides,with binding activities (expressed by IC50 values) ranging from 1.67 μg/L to 42.71 μg/L.All 6 phenylurea herbicides contain a common moiety and three different substitutes.

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