Type 2 innate lymphoid cells promote lung fibrosis

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户:hgscmey
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Background: Idiopathic pulmonary fibrosis (IPF) is a devastating treatment-refractory interstitial lung disease of unknown origin.Although the pathogenic mechanism of IPF is not fully understood, lung histology and bronchoalveolar lavage (BAL) show inflammatory cytology, including neutrophils, lymphocytes, macrophages, etc., which are thought to contribute to fibrogenesis.
其他文献
  目的:探讨RCAN1在鼠伤寒沙门氏菌诱导的肠炎中的作用方法:应用H&E染色方法观察小鼠盲肠组织的病理变化;应用ELISA方法检测小鼠盲肠部位炎性细胞因子和趋化因子结果:本实验以
会议
  Purpose: The mechanism regulating gastrointestinal epithelial barrier remains poorly understood.We herein demonstrate that AIM2 contributes to the maintaina
会议
  研究背景:脑中风是各种原因导致脑动脉血流中断,局部脑组织发生缺血缺氧性坏死而出现相应的神经功能缺陷。近年来脑中风发病率在全球范围内呈持续上升的趋势,而血管生成是
  Purpose: Systemic lupus erythematosus (SLE) is a complex, multiple organs involved, potentially fatal disease and also the prototype of other autoimmune dis
会议
  Innate lymphoid cells (ILCs) function in producing effector cytokines in response to pathogenic infections.However, the roles and related mechanisms of the
会议
  Fibrosis is a consequence of chronic inflammation and the persistent accumulation of extracellularmatrix, forwhich the cycle of tissue injury and repair bec
会议
  研究背景:巨噬细胞和树突状细胞(DC)在抵抗病毒感染的宿主天然免疫中占有重要的位置.它们不仅是HIV-1所攻击的主要宿主细胞之一,而且可以把病毒向其他组织传播并维持病毒的
  目的:急性肺损伤(ALI)是由肺部感染、吸入性肺炎或者肺外部因素等造成的肺部间接损伤引起的,由损伤诱发的炎症反应在ALI发展中发挥了重要的作用。临床上遏制全身失控性炎
会议
  Background: Liver diseases caused by Schistosoma japonicum(Sj) infection is one of the most serious pathological changes.Liver inflammation underlies infect
  研究背景:pDC细胞(plasmacytoid dendritic cell)是一种骨髓来源的细胞,在机体受到病原入侵时,可以通过分泌大量的I型干扰素或者作为抗原呈递细胞来起到杀伤作用,它强大的能
会议