The protective effects of remifentanil preconditioning against hypoxia reoxygenation injury in cultu

来源 :中华医学会第22次全国麻醉学术年会 | 被引量 : 0次 | 上传用户：zql0913

【摘要】

：

The cardioprotective effects of remifentanil preconditioning (RPC) against ischemia reperfusion injury have been demonstrated in intact and isolated rat hearts.1,2 This study aimed to investigate the

【作者】

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H.Wu S.F.He H.J.Zhu Y.Zhang

【机构】

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Department of Anesthesiology, Second Affiliated Hospital of Anhui Medical University, Hefei, China

【出处】

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中华医学会第22次全国麻醉学术年会

【发表日期】

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2014年11期

【关键词】

：

Remifentanil preconditioning Cardiomyocytes Hypoxia/reoxygenation injury Opioid

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The cardioprotective effects of remifentanil preconditioning (RPC) against ischemia reperfusion injury have been demonstrated in intact and isolated rat hearts.1,2 This study aimed to investigate the protective effects of RPC against hypoxia/reoxygenation (H/R) injury in cultured adult rat ventricular myocytes, and its mechanisms involving opioid receptors and phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT), extracellular signal-regulated kinase (ERK) signaling pathways.

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The protective effects of remifentanil preconditioning against hypoxia reoxygenation injury in cultu

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