Therapeutic Efficiency of Autologous-tumor cell-derived Microparticles Packaging Chemotherapeutic Dr

来源 :2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议 | 被引量 : 0次 | 上传用户:chenken2725115
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  目的 Refractory malignant pleural effusion presents a considerable clinical challenge,which causes dyspnea and short average lifespan of cancer patients in weeks.Lung cancer is a most common reason for MPE with an incidence up to 1/3,and the lung cancerpatients in stage Ⅳ with MPE usually have the shortest life span(three months in average).According to the BTS Pleural DiseaseGuideline(2010),all the recommended local treatments of MPE are all palliative methods,including chest tube insertion andregular drainage,regularly and pleurodesis with sclerosing agents,such as talc.So Thus,it is urgent to search for a more effective,safe,effective and individualized treatment therapy to treat the lung cancer patients with MPE in clinic.
其他文献
目的 肿瘤相关性血小板减少症的处理及预防方法 临床如使用血小板生成素预防CIT发生,对于采用吉西他滨+顺铂化疗方案发生CIT的患者,再次采用吉西他滨+顺铂方案化疗时,建议在吉西他滨注射后48小时内[3]开始皮下注射血小板生成素类药物,此后隔日皮下注射1次,对采用其他方案化疗的患者,如上一周期发生CITⅢ级以上者,可在血小板最低值出现前5天开始注射促血小板生成素类药物。结果 避免或减轻CIT的出现。
目的 探讨长期吸入激素加长效β2激动剂的稳定期中重度COPD患者联合应用噻托溴胺对呼吸困难症状及肺功能的改善作用.方法 单中心,随机,平行对照研究.60例应用吸入激素加长效β2激动剂治疗超过1年的稳定期中重度COPD患者(排除哮喘及ACOS患者)随机分为2组,吸入激素加长效β2激动剂治疗组(A组)30例,吸入激素加长效β2激动剂联用噻托溴胺(B组)30例,随机入组后治疗3个月,治疗前及治疗后采用呼
目的 Decreased expiratory airflow measured by spirometry is the prerequisite in establishing a diagnosis of asthma,but studieshave revealed that forced expiratory volume in one second(FEV1)was not assoc
目的 Knowledge of the molecular mechanisms on malignant tumors is very critical for the development of new treatmentstrategies like molecularly targeted therapies.In last five years,many investigations
目的 Endostar is a new potent endogenous angiogenic inhibitor with implicated antitumor activity.This study is to investigatewhether thoracic perfusion of Endostar could be used to control malignant ple
目的 阻塞性睡眠呼吸暂停综合征(OSAHS)发病率高、危害较大,其与肺功能关系密切,但仍存在一些争议.首先,OSAHS患者肺功能改变:流量-容积曲线虽有特征表现,但不是有效的诊断OSA的初筛试验.FRC、ERv、FEV1%、FVc、MVV等可能与OSA有关,但存在争议.
目的 Fibrosing mediastinitis is a rare disease.It was thought to be related with prior granulomatous mediastinal infection,such ashistoplasmosis or tuberculosis.Most cases were reported in histoplasmosi
目的 Detect the dynamic change of expression of peroxisome proliferators activated receptor γ(PPAR-γ)in patients withpulmonary thromboembolism(PTE),explore the possible role of PPAR-γ from an acute PTE
目的 探讨激活PPAR-γ是否通过下调miR-21抑制TGF-β1诱导的气道平滑肌细胞(ASMCs)增殖。方法 原代大鼠ASMCs分为对照、TGF-β1、miR-21抑制剂NC+TGF-β1、miR-21抑制剂+ TGF-β1组,BrdU测细胞增殖,RT-PCR测miR-21水平,Western blot 测FoXO1(核)、cyclin D1蛋白水平;吡格列酮(PPAR-γ激动剂)预处理后给予T
目的 B7-H4 is expressed in many different human cancers but its role in malignant pleural tissue has yet to be established.Theincreasing incidence and poor outcome associated with malignant pleural effu