scAAV5-mediated Gene Transduction of Novel CD40L Mutant Enhances Direct Antitumor Effects in Lung Ca

来源 :2015中国老年医学和老年健康产业大会 | 被引量 : 0次 | 上传用户:tourena
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
BACKGROUND: CD40L gene therapy offers an attractive option for lung cancer because of its multiple antitumor activities.However, membrane-bound CD40L may be proteolytically cleaved to form soluble CD40L (sCD40L), which leads to adverse effects.
其他文献
OBJECTIVE: To understand the epidemiology of nonalcoholic fatty liver disease (NAFLD) in the elderly and to find the risk factors for NAFLD.METHODS: Eight hundred and five elderly people with the age
会议
OBJECTIVE: To evaluate the difference in isokinetic strength of knee muscles between patients with knee osteoarthritis (KOA) aged over 80 and matched healthy controls, and to establish the correlation
会议
OBJECTIVE: To compare cognitive funtion among patients with late-life depressive disorder, amnestic mild cognitive impairment patients and normal controls.METHODS: We recruited 38 patients with depres
会议
OBJECTIVE: This study aimed to describe the situation of hospitalized elderly surgical patients and their associated perioperative mortality at our center, so as to develop strategies to reduce periop
会议
OBJECTIVE: To explore the pattern of volume changes of the whole brain gray matter in patients with late-life depressive disorder and amnestic mild cognitive impairment by voxel-based morphometry (VBM
会议
BACKGROUND: Although HMGA, SIRT1 and Ki-67 proteins appeared to occur widely in different cancers, few studies have investigated the definite role of these proteins in lung cancer.The aim of this was
会议
OBJECTIVE: High-salt intake and family history of hypertension are involved in the pathogenesis of hypertension and vascular remodelling.This study examined the interactions of high salt and family hi
会议
BACKGROUND: Ability of liver can remove harmful substances and make liver cells proliferate to maintain its functions.Elders are apt to be affected by stress result to liver injury.This study was to d
会议
OBJECTIVE: The remodeling of gallbladder artery in hypertensive patients and its underlying mechanisms are poorly understood.The present study aimed to observe the morphological and histological chang
会议
OBJECTIVE: To investigate whether the structure, ultrastructure and hydrogen potassium adenosine triphosphate (H+/K+ AT-Pase) activation of beagle dogs parietal cells were associated with aging.
会议