目的 We previously reported that GOLPH3 promotes glioma progression by inhibiting EGFR endocytosis and degradation,leading to EGFR accumulation and PI3K-AKT pathway overactivation.
Objective Clear cell renal cell carcinoma(ccRCC),the most common subtype of renal cell carcinoma,can easily invade local tissues and metastasize,and is resistant to currently available treatments.Rece