目的 Kleine-Levin syndrome (KLS) is a rare disorder primarily occur in adolescents with a tendency of four times higher morbidity in male than female, is characterized by intermittent episodes of hypersomnolence, cognitive and behavioral disturbances and hyperphagia.Limited research has been conducted, especially in Chinese patients.Our case describes a 14-year-old Chinese girl with recurrent hypersomnia.She experienced four attacks before diagnosed, behaved normally between each attack, and present down mood before each attack.She was seen by a psychiatrist with no focal findings and then monitored in our sleep center using polysomnography during an episode.The result was negative for sleep apnea and the electroencephalogram signals showed no epileptiform activity.During first three episodes, she was evaluated without a clear diagnosis, and therefore unable to attend school.She was then diagnosed and treated at our Sleep Disorders Center during her fourth attack.The patient was treated with methylphenidate 10 mg daily for 1 month and was under weight controll and behavioral Intervention treatment after withdrawn from medicines.She didnt experienced attack again and was followed-up by our Center regularly.