Objective To discuss the effect on spinal cord blood supply after simultaneous thoracic and abdominal endovascular aortic repair for lesions involving both descending and abdominal aorta.Methods A retrospective analysis of the lesion February 2009 to-January 2013 the center hospitalized involving the thoracic aorta and abdominal aorta in patients, a total of 18 cases (male 17 cases, female 1 cases, average age (61.13±≥7.25), in which aortic combined with abdominal aneurysm in 10cases, PAU combine abdominal aneurysm in 5 cases,PAU in aortic and abdominal aorta in 2 cases and AD combine abdominal aneurysm in 1 case.The open bilateral side of femoral artery puncture, completion of endovascular repair of aortic stent, which according to disease (1 stent or implantation of 2 covered stent, overlapping),and one-stent-graft separating-stent-graft for abdominal aorta disease.Results 1 cases of spinal cord injury (5.6%), the nutrition of the dewatering machine nerve recovery after treatment, the average follow-up of 3-24 months, all patients no stent leakage and stent displacement complications.Conclusion The curative effect is satisfied that the treatment for lesion involve the descend aorta and abdominal aorta.Although avoiding the paraplegia completely is impossible, its application will be more and more widely, it is worthy of clinical application.