【摘 要】
：
Either endothelial cells covering the inner site of a vessel as well as circulating progenitor cells originating from the bone marrow or other organs may se
【机 构】
：
DepartmentofClinicalBiochemistry,TheJagiellonianUniversityMedicaCollege,Poland
【出 处】
：
2005 World DNA and Genome Day(2005中国(大连)国际DNA和基因组节大会)
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Either endothelial cells covering the inner site of a vessel as well as circulating progenitor cells originating from the bone marrow or other organs may serve as source of endothelial cells for angiogenesis in an adult organism.Beside the growth factors (such as:VEGF,bFGF,TGFb,PDGF) or cell/matrix (integrins),cell/cell (VE cadherins,catenins,endoglins,ephrins its receptors and Jagged/Notch pathway) as well the nutrition-related compounds could regulate the most important steps of angiogenesis like proliferation,migration and differentiation.In our experiments we wanted to investigate regulatory influence of compounds from daily diet such as fatty acids and beta-carotene on gene expression,proliferation,migration and differentiation on endothelial progenitor cells (EPC) in comparison to early differentiated endothelial cells (HUVEC).
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