目的:Perilipin(Peri)是包被在脂滴周围的一种蛋白,保护细胞内的脂滴不被分解。尽管perilipin在动脉粥样硬化(AS)病变中增多,且和巨噬细胞共定位,但其在动脉粥样硬化发生中的作用尚不明确。我们应用对动脉粥样硬化敏感的ApoE-/- Purpose: Perilipin (Peri) is a protein coated around lipid droplets that protects lipid droplets within cells from being broken down. Although perilipin increases in atherosclerotic lesions and co-locates with macrophages, its role in the development of atherosclerosis is unclear. We applied ApoE - / - that is sensitive to atherosclerosis