The UNC5D dependence receptor intracellular domain regulatespro-apoptotic transcription via nuclear

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户：Lynn_lin

【摘要】

：

【作者】

：

Yuyan Zhu Meng Yu Yixia Wang Yifu Chen Xiaojun Man

【机构】

：

Department of Urology, First Hospital of China Medical University, Shenyang, People's Republic of C

【出处】

：

中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议

【发表日期】

：

2014年3期

【关键词】

：

dependence receptor UNC5D apoptosis neuroblastoma

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Spontaneous regression of neuroblastoma (NB) resembles the developmentally regulatedprogrammed cell death (PCD) of sympathetic neurons.Regressing tumor cells express highlevels of the nerve growth factor (NGF) receptors TRKA and p75NTR and are dependent onNGF for survival; however, the underlying molecular mechanism remains elusive.

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The UNC5D dependence receptor intracellular domain regulatespro-apoptotic transcription via nuclear

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