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5. Coupled Global and Targeted Lipidomics and proteomics in acs-3 mutant C.Elegans with Different Stage

Coupled Global and Targeted Lipidomics and proteomics in acs-3 mutant C.Elegans with Different Stage

来源 :第八届中国蛋白质组学大会 | 被引量 : 0次 | 上传用户：acmevb

【摘 要】

：

Acyl-CoA synthases play critical role in lipid synthesis and breakdown.Loss of ACS family of enzymes usually causes embryo lethal,lipids uptake alternation,and cuticle defect.Here we show that ACS-3 f

【作 者】

：

Yi Wang Huali Shen Pengyuan Yang Min Han 

【机 构】

：

Howard Hughes Medical Institute and University of Colorado at Boulder,Colorado,USA,80302;Department

【出 处】

：

第八届中国蛋白质组学大会

【发表日期】

：

2013年11期

【关键词】

：

lipidomics proteomics NPLC-MS ACS-3 acyltransferase 

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Acyl-CoA synthases play critical role in lipid synthesis and breakdown.Loss of ACS family of enzymes usually causes embryo lethal,lipids uptake alternation,and cuticle defect.Here we show that ACS-3 functions by combination of comparative lipidomics study and proteomics study on ACS-3(-) C.elegens with different stages.

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