【摘 要】
：
Endothelin receptor antagonist (ERA) therapy, has been shown to be well tolerated and effective in improving pulmonary arterial hypertension (PAH) symptoms
【机 构】
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Manchester Royal Infirmary UK
论文部分内容阅读
Endothelin receptor antagonist (ERA) therapy, has been shown to be well tolerated and effective in improving pulmonary arterial hypertension (PAH) symptoms in patients with Eisenmenger syndrome but data from longer-term studies are lacking.Prospectively coliected data from adult patients with PAH-CHD (with and without Down syndrome) initiated on ERA over a 3 year period were analyzed.Parameters measured before ERA initiation and ateach follow-up (1 month and 3, 6, 9, 12, 18, and 24 months) included exercise capacity (6-minute walk distance [6MWD]), pretest oxygen saturation, liver enzymes, and hemoglobin.
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