Objective:Dilated cardiomyopathy(DCM)is characterized as the left ventricular dilatation,dysfunction and myocardial fibrosis.Cardiac magnetic resonance imaging can noninvasively assess remodeling of left ventricular included structure,function and myocardial fibrosis.This study investigate the association between the dysfunction and myocardial fibrosis of left ventricular remodeling in patients with dilated cardiomyopathy using cardiac magnetic resonance imaging(CMR).Materials and Methods:1.Twenty-two patients who have been diagnosed as dilated cardiomyopathy clinically are inclusion in the department of Cardiology from March 2014 to March 2016.All patients were received the CMR examination.2.The myocardial fibrosis and the involved segments of left ventricular were found in late gadolinium enhancement(LGE).According to myocardial fibrosis,the patients with DCM were divided into three groups.Group A: Non-fibrosis group.Group B: Low-grade fibrosis group(involved cardiac segments<5).Group C: High-grade fibrosis group(involved cardiac segments≥5).3.The structure and function of left ventricular were measured in CINE.Those parameters were included left ventricular enddiastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),left ventricular ejection fraction(LVEF),stroke volume(SV),cardiac output(CO),cardiac index(CI),left ventricular myocardial mass(LVMM),left ventricular end-diastolic dimension(LVEDD)and Sphericity index(SI).Compare those index among the three groups.Result:1.In all patients with DCM,there were 6(6/22)patients without myocardial fibrosis(Group A=6),11 patients with lowgrade fibrosis(Group B=11)and 5 patients with high-grade fibrosis(Group C=5).2.The myocardial fibrosis were involved as total 80 segments in DCM patients with myocardial fibrosis.The most frequently involved cardiac segment were basal anteroseptal(13/16)segment and basal inferoseptal segment(13/16).3.There were statistically significant differences on LVEDV,LVESV,LVEF,LVMM,LVEDD and SI among those three groups.In the comparison of LVEDV,LVESV,LVMM and LVEDD,Group A < Group B < Group C while in the comparison of LVEF and SI,Group A > Group B > Group C.4.There were non-statistically significant differences on SV,CO and CI among those three groups.Conclusion:1.CMR,as a noninvasively technique,can comprehensive evaluate the heart and provide more valuable information for patients with DCM.2.LGE can not only find myocardial fibrosis but also evaluate the severity while CINE can accurate measured the functional index of left ventricular.Combined these two techniques could reflect the left ventricular remodeling in patients with DCM.3.The more numbers of myocardial fibrosis involved cardiac segments,the worse cardiac function,the more serious the degree of ventricular remodeling in patients with DCM.