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5. Enlargement of Axial Length and Alerted Ultrastructural Features of Sclera in a Mutant Lumican Trans

Enlargement of Axial Length and Alerted Ultrastructural Features of Sclera in a Mutant Lumican Trans

来源 :首都医科大学第三届研究生学术论坛 | 被引量 : 0次 | 上传用户：killlikk

【摘 要】

：

Purpose: Lumican gene (LUM) is a candidate gene of myopia in MYP3 locus, and lumican is one of the major extracellular matrix components of the sclera.A mutant lumican (Leu 199 Pro, L199P) transgenic

【作 者】

：

Yan-Zheng Song Yan-Yan Zhao Ming-Shen Sun Jun Tao Yan-Chuang Liang Yan-Qiu Yu Ling Ma Junfeng Hao Jianhua Wang Feng-Ju Zhang 

【机 构】

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From the Beijing Tongren Eye Center, Beijing Tongren Hospital,Capital Medical University;Beijing Oph

【出 处】

：

首都医科大学第三届研究生学术论坛

【发表日期】

：

2015年9期

【关键词】

：

Lumican mouse transgenic myopia sclera collagen 

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　　Purpose: Lumican gene (LUM) is a candidate gene of myopia in MYP3 locus, and lumican is one of the major extracellular matrix components of the sclera.A mutant lumican (Leu 199 Pro, L199P) transgenic mouse model was established to investigate the axial length changes and ultrastructural features of sclera.

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