【摘 要】
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Backgrounds SP-D knockout (SP-D-/-) mice exhibit an increase in the number and size of airway macrophages, peribronchiolar inflammation, increases in metalloproteinase activity, and development of emp
【机 构】
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the Fifth People's Hospital of Shanghai, Fudan University;Rutgers, The State University of New Jers
【出 处】
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2014中华医学会呼吸病学年会暨第十五次全国呼吸病学学术会议
论文部分内容阅读
Backgrounds SP-D knockout (SP-D-/-) mice exhibit an increase in the number and size of airway macrophages, peribronchiolar inflammation, increases in metalloproteinase activity, and development of emphysema.Increased nitric oxide metabolic is involved in the process of this pathology.We have previously shown that disruption of iNOS-NO loop in SP-D-/-mice reverses inflammation with the alteration of macrophage activation.
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