【摘 要】
：
Micelles self-assembled from amphiphilic copolymers have become one of the most promising carriers of anticancer drugs, manifesting several attractive features such as the core-shell structure to effe
【机 构】
：
Key Laboratory of Advanced Technologies of Materials, Ministry of Education of China,School of Mater
【出 处】
：
纳米药物及纳米生物技术国际学术大会暨中国药学会纳米药物专业委员会成立大会
论文部分内容阅读
Micelles self-assembled from amphiphilic copolymers have become one of the most promising carriers of anticancer drugs, manifesting several attractive features such as the core-shell structure to effectively protect and enhance the water solubility of anticancer drugs in the core.
其他文献
In this work, poly(ethylene oxide)-b-poly(N-methacryloyl-N-(tert-butyloxycarbonyl)cystamine)(PEO-b-PMABC) diblock copolymers were developed by reversible addition-fragmentation chain transfer (RAFT) p
Magnetic resonance imaging (MRI) probes are the important tools for discovering small pathological changes with functionality analysis.Probe structural design, functionality,multimodality, and applica
Aptamers are single-stranded nucleic acids having molecular recognition properties similar to antibodies, and isolated by in vitro selection and amplification process, SELEX.Aptamer engineering includ
Many aromatic and planar mutagens can inhibit both transcription and replication of DNA and cause cytotoxicity and mutations by intercalating into the base pairs of DNA.To date, perylene derivatives h
While thermo-chemotherapy has proved to be effective in optimizing the efficacies of cancer treatments, traditional chemotherapy is subject to adverse side effects and heat delivery is often challengi
Fluorescent imaging in the second near-infrared window (NIR-Ⅱ, 1.0～1.4 μm) is appealing due to minimal autofluorescence and negligible tissue scattering in this region, affording maximal penetration d
Nano-scaled drug delivery systems have been attracting great attention in cancer treatment.However, the abnormal blood supply and highly heterogeneous microenvironment of tumor bring tremendous diffic
Amphiphilic molecules are designed using peptides as targeting moiety and alkyl group as lipophilic segment of molecules.These molecules self-assemble to form micelles in an aqueous environment with p
Multidrug resistance (MDR) is a major challenge for the success of cancer chemotherapy.Limited tumor diffusion and penetration of chemotherapeutic drugs accounts for the occurrence of cancer MDR.
Nanoscale particles have become promising materials in various biomedical applications,however, in order to stimulate and facilitate these applications, there is an urgent need for a better understand