Overexpression of Sirt7 Promotes Human Colorectal Cancer Cell Colony Formation Through Inhibiting SE

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户：jerry8006

【摘要】

：

　　Background: Sirt7,a member of the sirtuin family,deacetylates Histone H3K18ac thus maintaining oncogenic transformation.But less is known about the relation

【作者】

：

Yang Li Shun Zhang Dan-dan Huang Jing Lin Ting Cai

【机构】

：

NingboNo.2Hospital,Ningbo,315010NingboNo.2Hospital,Ningbo,315010;StemCellLaboratory,NingboNo.2Hospit

【出处】

：

中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议

【发表日期】

：

2018年10期

【关键词】

：

Colorectal Cancer Sirt7 SESN2 Sp1 Autophagy

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　　Background: Sirt7,a member of the sirtuin family,deacetylates Histone H3K18ac thus maintaining oncogenic transformation.But less is known about the relationship between colorectal cancer development and progression.Here we explore the role of Sirt7 in colorectal cancer cell autophagy and colony formation.

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Overexpression of Sirt7 Promotes Human Colorectal Cancer Cell Colony Formation Through Inhibiting SE

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