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Background: The expression of Survivin,an inhibitor of apoptosis can be seen in most tumors and is correlated with the angiogenic factor vascular endothelial growth factor(VEGF).But little is known about their contribution in small-cell lung cancer (SCLC).This study was designed to investigate the expression of Survivin and VEGF in SCLC,and to explore their correlation with clinical-pathological feature and prognosis.