Phospholipids are recognized as non-allergic,bio-friendly permeation enhancers due to their similarity to the constituents of biomembranes.Therefore,liposomes become versatile carriers for drug delivery because of their structural and functional integrity [1].To date,several methods have been reported for the fabrication of liposomes.However,these methods are hard to apply for mass production due to the use of harmful organic solvents and the multi-step fabrication process.