DNA binding,cytotoxicity and apoptosis induction activity of mono/di-nuclear Zn complexes constructe

来源 :第九届全国无机化学学术会议 | 被引量 : 0次 | 上传用户:asd03071128
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Great efforts are being made to develop new-type “non-classical” platinum-containing complexes with better efficiency for exploring cancer therapy to circumvent the drawbacks what platinum complexes induced in clinical [1,2].
其他文献
  中药成分大黄素型蒽醌类对多种肿瘤细胞具有抗增殖能力,但是其抗肿瘤活性较低。以大黄素型蒽醌类为先导化合物,对其在结构上引入金属元素形成稳定配合物的抗肿瘤药性研究具
  Metal complexes have been widely studied as potent proteasome inhibitors.The 20S proteasome,the main component of the ubiquitin proteasome system,has been o
会议
  A novel Ag@C core-shell structural nanosphere was prepared with Au nanoparticles decorated onto the surface.Ag@C nanospheres were firstly synthesized throug
会议
  A new dual-core ruthenium complex,[Ru2(pip-An)(bpy)4](PF6)4 [where pip-An = 9,10-bis(4-(1H-imidazo[4,5-f][1,10]phenanthrolin-2-yl)phenyl)anthracene],has bee
会议
  Photodynamic therapy(PDT)has gained extensive attention as an emerging treatment modality.To date,upconversion nanoparticles conjugated with photosensitizer
会议
  A novel 1D supramolecular Cd(Ⅱ)complex has been synthesized and characterized as [(CdL2·4H2O)·4H2O](1)using 4-(acetylamino)benzoate(HL).
会议
会议
  二硫代氨基甲酸类化合物具有很强的金属螯合能力,而且二硫代氨基甲酸类具有显著的抗癌活性[1]。利用不同取代基团的二硫代氨基甲酸配体稳定金属离子,本文合成了一系列二硫
  目前,在临床上癌症的治疗手段主要包括手术、化疗与放疗等,但是仍然存在治疗效果不理想,副作用大以及耐药性等问题,因此,发展新的治疗手段势在必行。
  金属卟啉配合物在生物成像、生物探针和抗癌等方面具有广泛的应用,因此越来越受到各国科学家们的关注。但在生物和医学方面发展的一个主要障碍是水溶解性,通过引入亲水取代