Characteristics, origin and structure of conductive pilus in Geobacter species

来源 :第七届全国生物信息学与系统生物学学术大会 | 被引量 : 0次 | 上传用户：jxj860205

【摘要】

：

【作者】

：

束传军肖可严沁孙啸

【机构】

：

东南大学生物科学与医学工程学院,生物电子学国家重点实验室,南京,200196

【出处】

：

第七届全国生物信息学与系统生物学学术大会

【发表日期】

：

2016年8期

【关键词】

：

Conductive pilin structure phylogenetic analysis gene fission molecular dynamics

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Background: Geobacter sulfurreducens can transfer electrons to extracellular electron acceptors through its pilus[1-3].The G.sulfurreducens pilus,composed of thousands copies of monomers has been reported to have metallic-like conductivity[4-5].The structure of G.sulfurreducens pilus and the mechanism for electron transfer in Geobacter still remain unknown[3-6].Constructing the detailed structure of pilus remains a challenge due to the insolubility of monomers,surface appendages and the heterogeneity of assembly[5-8].

其他文献

Multiple dimensional feature space for protein interface residue prediction

Protein-protein interacts through specific interface residues to execute biological functions.Correctly understanding the mechanisms of interface recognition and predicting the interface residues are

会议

HMMCAS: a web-based tool for the identification of Cas proteins

The CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated proteins) adaptive immune systems are discovered in many bacteria and most archaea.These defence systems are

会议

Cas proteinsCRISPR-Cas systemhidden Markov modelssimilarity search

QM/MM Multiscale Simulations Reveal Biosynthetic Mechanism of Lanosterol

Enzymatic catalysis mechanism,which is the central to understand the biogenesis and diversity of natural products,would shed bright light on the rational drug design and protein engineering.The biosyn

会议

QM/MMMultiscale SimulationEnzymatic CatalysisBiosynthesis

Peptide Indirectly Induce the Long-Range Conformational Response in the PBD Dimerization Process: A

Modular protein interaction domains form the building blocks of cell signaling pathways.Many of them,known as peptide recognition domains,mediate protein-protein interactions by recognizing short,line

会议

indirectly peptide-mediated proteinPBD domainpPon peptidelong-range conformat

Negative GO Annotations Selection using Ontology Structure

Predicting the biological functions of proteins is one of the key challenges in the post genomic era.Computational models have demonstrated the utility of applying machine learning methods to predict

会议

GOOntology StructurePositive AnnotationsNegative Annotations

Genome-wide Protein Function Prediction via Multi-instance Multi-label Active Learning

As the number of sequenced genomes rapidly grows,there are a large number of proteins with unknown function in new genomes.Active learning methods can assist biologists for selecting the most valuable

会议

Protein Function PredictionMulti-instance Multi-label LearningActive Learning

Rational design of a carboxylic esterase RhEst1 based on computational analysis of substrate binding

A new carboxylic esterase RhEst1 which catalyzes the hydrolysis of (S)-(+)-2,2-dimethylcyclopropanecarboxylate (S-DmCpCe),the key chiral building block of cilastatin,was identified and subsequently cr

会议

carboxylic esterasemolecular dynamics simulationrational designstructural mec

Utilization of order factor and principal component analysis to predict protein subcellular localiza

With the coming of the post-genomic age,protein sequences have increased rapidly.It has been a topic issue about using intelligent calculation method to predict the protein subcellular localization.In

会议

Protein subcellular localizationPseAAC-order factorPCASVM

Accurate prediction of protein fold type by integration of template-based assignment and ab-initio m

Prediction of fold type is a critical step in protein structure prediction[1].we developed two algorithms,HH-fold and SVM-fold for protein fold type prediction.HH-fold is a template-based fold assignm

会议

Protein Structure PredictionProfile-Profile AlignmentFold Recognition

Mechanism of the Self-Assembly of Calcitonin

Calcitonin,a hormone with the ability of reducing serum calcium,is a 32 amino-acid peptide.It has been experimentally observed that calcitonin can undergo self-assembly to form nanoparticles under som

会议

calcitoninself-assemblymolecular dockingbinding free energyenergy decomposit

Characteristics, origin and structure of conductive pilus in Geobacter species

与本文相关的学术论文