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  5. Confidence regions for Treatment Effects in Subgroups in Biomarker Stratified Designs

Confidence regions for Treatment Effects in Subgroups in Biomarker Stratified Designs

来源 :上海交通大学 | 被引量 : 0次 | 上传用户：yuxuan423
【摘 要】
：
Subgroup analysis has important applications in the analysis of controlled clinical trials.Sometimes the result of the overall group fails to demonstrate that the new treatment is better than the cont
【作 者】
：
Fang Wan Cornelia Kunz Thomas Jaki 
【机 构】
：
Lancaster University,Lancaster,LA1 4YF.United Kingdom
【出 处】
：
上海交通大学
【发表日期】
：
2016年4期
【关键词】
：
Confidence region treatment effects subgroup biomarker stratified design 
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　　Subgroup analysis has important applications in the analysis of controlled clinical trials.Sometimes the result of the overall group fails to demonstrate that the new treatment is better than the control therapy,but for a subgroup of patients the treatment benefit may exist; or sometimes the new treatment is better for the overall group but not for a subgroup.
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