Curcumin inhibits EMMPRIN and MMP-9 expression through AMPK and MAPK signaling in PMA induced macrop

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Background In coronary arteries,plaque disruption,the major acute clinical manifestations of atherosclerosis,leads to a subsequent cardiac event,such as acute myocardial infarction (AMI) and unstable angina pectoris (UA).Monocyte-derived macrophages are known to play a critical role in the initiation and progression of atherosclerosis.
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