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  5. Genetic characteristics of the PB1-F2 proteins from different subtypes and host origins of influenza

Genetic characteristics of the PB1-F2 proteins from different subtypes and host origins of influenza

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户：vvchan
【摘 要】
：
Background: The PB1-F2 is the 11th protein of influenza A virus, encoded by the +1 alternate open reading frame (ORF) in the PB1 gene and previously reported to be a virulence factor that could contri
【作 者】
：
束传军 王嘉 朱华晨 管轶 
【机 构】
：
汕头大学医学院国际感染与免疫研究所,广东汕头515041 汕头大学医学院国际感染与免疫研究所,广东
【出 处】
：
第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会
【发表日期】
：
2014年4期
【关键词】
：
influenza A virus PB1-F2 pathogenicity truncation adaptation host 
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　　Background: The PB1-F2 is the 11th protein of influenza A virus, encoded by the +1 alternate open reading frame (ORF) in the PB1 gene and previously reported to be a virulence factor that could contributed to the viral pathogenicity.To understand how the PB1-F2 protein evolved in different suptypes of influenza A viruses in different hosts, molecular characteristics of this protein were analyzed.
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