Human papillomavirus E6 and E7 fusion proteins with bacterial exotoxin exhibited anticancer efficacy

来源 :10th IST Asia Pacific Congress on Animal , Plant and Microbi | 被引量 : 0次 | 上传用户:ynl007
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Cervical cancer is highly associated with human papillomavirus (HPV) infection.Two HPV oncoproteins E6 and E7 are constantly expressed in cervical cancers and represent ideal tumor-specific target antigens for immunotherapy.We generated fusion proteins by combining domains of Pseudomonas aeruginosa exotoxin A (PE)with E7 and E6,respectively.
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