Study Design.An in vivo animal study.Objective.To histologically and radiographically assess the reparative effect of a combined use of platelet-rich plasma (PRP) and bone marrow-derived mesenchymal s
目的:通过不同量金黄色葡萄球植入兔桡骨,观察影像学及组织学变化,探讨兔桡骨骨髓炎动物模型中金黄色葡萄球菌的合适剂量.方法:35只成年雄性新西兰兔双侧桡骨制造骨窗,注入不同量(1×104～1×109CFU)的金黄色葡萄球菌作为实验组(A～F组),对照组注入0.1ml生理盐水.分别于术后当日、术后两周、四周行X线及CT扫描检查.术后4周完成影像学评分后,处死兔取出桡骨完成肉眼观察评分,再作细菌培养、组
目的：通过比较大鼠动静力失衡颈椎退变模型中C4/C5、C5/C6、C6/C7三个椎间盘高度、软骨终板磨损面积率和组织学评分，研究该模型对不同节段椎间盘退变的影响。方法：24只3月龄雌性SD大鼠随机分为实验组和对照组。实验组大鼠横向切断颈背部部分肌肉以及相关韧带。术后12、18、24周分三次取颈椎标本。μCT扫描颈椎标本。测量C4/C5、C5/C6、C6/C7椎间高度。使用IPL程序，分离椎体。保存
With the development of stem cell transplantation and intravital microscopy, there is a demand for low toxicity cell-labeling probes for in vitro and in vivo studies.Water-soluble perylene tetracarbox
Background For the mechanical strength, biocompatibility and sterilizability, silk fibroin is well utilized as a natural bone regenerate material.Methods To improve the mechanical character and reinfo
目的:观察骨髓间充质干细胞(Bone mesenchyal stem cells,BMSCs)移植对脊髓损伤大鼠体内激素及海马区α-氨基羟甲基恶唑丙酸(α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid,AMPA)影响以阐明BMSCs移植治疗大鼠脊髓损伤的潜在抗慢性应激作用.方法:将48只成年雄性SD大鼠,按随机数字平均标记为A对照、B模型、C
Purpose: To determine the signaling pathways involved in chondrocyte migration and their effects on cartilage integration in autologous chondrocyte implantation.
目的：探讨p38MAPK与假体周围颗粒诱导炎性骨溶解之间的关系.方法：钛颗粒刺激体外培养的RAW246.7细胞,用SB203580干预,Western blot检测p-p38mapk蛋白表达,ELISA检测细胞分泌TNF-a,IL-6水平.结果：钛颗粒刺激细胞培养组(B组)比较于没有用颗粒刺激的正常培养组(A组),p-p38mapk蛋白含量,以及培养液上清中TNF-a,IL-6含量都明显升高(p＜
Introduction: Hydroxyapatite (HA) has been studied recently as a drug carrier in prevent implant infections due to its biocompatibility and osteoconductive properties, but most of these studies failed
Objective To study the osteogenic potential of SF/PLCL electrospinning material composited with bone mesenchymal stem cells (BMSCs) in repairing the radius defection in rabbits.Method Bone marrow was