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5. Human beta-defensin 1, a new animal toxin-like blocker of potassium channel

Human beta-defensin 1, a new animal toxin-like blocker of potassium channel

来源 :第12届生物毒素研究及医药应用学术大会 | 被引量 : 0次 | 上传用户：loveshdou

【摘 要】

：

The human β-defensin 2 (hBD2), as a Kv1.3 channel inhibitor with the unique molecular mechanism and novel immune modulatory function, suggests that human β-defensins are a kind of novel channel ligand

【作 者】

：

Jing Feng Zili Xie Weishan Yang Fang Xiang Yonghui Zhao Zhijian Cao Wenxin Li Zongyun Chen Yingliang Wu 

【机 构】

：

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072,China

【出 处】

：

第12届生物毒素研究及医药应用学术大会

【发表日期】

：

2015年5期

【关键词】

：

Kv1.3 channel human β-defensin 1 human β-defensin 2 endogenous blocker function 

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　　The human β-defensin 2 (hBD2), as a Kv1.3 channel inhibitor with the unique molecular mechanism and novel immune modulatory function, suggests that human β-defensins are a kind of novel channel ligands.Here, function and mechanism of the human β-defensin 1 (hBD 1) binding to potassium channels was investigated.

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