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Nuclear Power Plant ventilation system is the important system to NPP,among which safety related ventilation systems normal operation plays a key role in safety and reliable operation of NPP.Fans as power facilities have significant influence.Key components and failure modes affecting the reliability can be obtained by analyzing reliability of safety important ventilation system fans of NPP,which can be used to improve operation and maintenance strategy of NPP in operation and system reliability as well as provide support for system design and equipment optimization of new NPP.