Exercise Exerts Neuroprotective Effects on the Substantia Nigra Dopaminergic Neurons in MPTP Lesione

来源 :2011年第一届内分泌与代谢大会 | 被引量 : 0次 | 上传用户:guicailea
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Parkinsons disease (PD) is a progressive disease with a variety of symptoms such as the increased resistance, slowness of movement, hypokinesia and akinesia and so on.PD patients also typically develop a stooped posture and may lose normal postural reflexes, leading to falls.The central pathological feature of PD was the loss ofdopaminergic neurons in the substantia nigra.Recent studies from several laboratories have shown that exercise can have a beneficial effect in patients with PD and in rodent models of PD.
其他文献
The endocannabinoid system consists of two G protein-coupled receptors known as cannabinoid receptors CB1 and CB2; their endogenous ligands, the endocannabinoids; and the enzymes responsible for ligan
会议
Various membrane trafficking phenomena including those involving the interactions between endosomes and lysosomes are regulated by changes in [Ca2+] and related cell signaling pathways.These processes
会议
Inhibition ofaeyl-CoA:diaeyiglycerol acyltransferase-1 (DGAT-1), an enzyme that catalyzes the final committed step of triglyceride synthesis, represents a potential therapeutic entry point forthe trea
会议
In persons with type 2 diabetes mellitus (PWD2), therapeutic potential of continuous subcutaneous insulin infusion (CSII) is yet to be specified.The purpose of our open label on-going trial is to comp
会议
INGAP is a member of the Reg family of proteins.It has been implicated in various settings of endogenous pancreatic regeneration, and may also play an important role in maintaining beta cell function.
会议
The induction of protective antibodies against microbial agents by vaccination has been the most effective medical intervention in human hystory, leading to the eradication, or lessening the strength
会议
Prior studies have established that a prolonged effect of hyperglycaemia exists on both micro-and macrovascular complications in types 1 and 2 diabetes.This deleterious extended effect is sometimes re
会议
The adverse condition of high glucose concentration in a person with diabetes is known to impair wound healing.A novel method for microvascular endothelial cell migration and wound healing has been de
会议
Chronic Hepatitis C viral infection (HCV) affects around 170 millions worldwide and is the leading indication for hepatic transplantation.Egypt has one of the highest prevalence of patients with HCV w
会议
Mammalian fatty acid 2-hydroxylase (FA2H) was recently identified and characterized.2-Hydroxy fatty acids (2-OHFA) generated by FA2H are utilized for synthesis of 2-hydroxysphingolipids, which are com
会议