Efficient approach to 2-hydroxy-2,3-dihydrofuran derivatives and its application for the synthesis o

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The 2-hydroxy-2,3-dihydrofuran moiety widely exist in many natural products and pharmacological molecules(e.g.,Auranfuron A and B,Siphonarienfuranone,Drimanes,Hydroxyfuranone),1,2 which exhibit excellent antifungal,antitumor,antibiotic,bacteriostatic and cytotoxic activities(Scheme 1).
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