Complement-Mediated Perivascular Inflammation Contributes to Vascular Injury in Hypertensive Mice

来源 :The Pulse of Asia 2015(第七届亚洲动脉年会) | 被引量 : 0次 | 上传用户：owenzhong2012

【摘要】

：

【作者】

：

Cheng-Chao Ruan Yu Ma Qian Ge Yan Li Ling-Ran Kong Dong-Rui Chen Fanghong Li Lixian Cheng Allan Z.Zhao Ding-Liang Zhu Ping-Jin Gao

【机构】

：

State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hyp

【出处】

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The Pulse of Asia 2015(第七届亚洲动脉年会)

【发表日期】

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2015年9期

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Rational: Macrophage polarization plays a pivotal role in the pathogenesis of hypertensive vascular remodeling.Our previous study has demonstrated that the expression of complement 3 (C3) dramatically increases in perivascular adipose tissue (PVAT) of deoxycorticosterone acetate (DOCA)-salt hypertensive model.

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Complement-Mediated Perivascular Inflammation Contributes to Vascular Injury in Hypertensive Mice

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