Interferon regulatory factor 4 (IRF4) regulates the transcription of genes essential for the differentiation and function of multiple Th/Treg subsets, including Th2, Th9, Thl7 and Treg.However, the mo
Background: Activation of CD4+T cells play a pivotal role in renal ischemia reperfusion injury.Galectin-9 (Gal-9) is a T-cell immunoglobulin domain and T mucin domain protein-3 (Tim-3) ligand, and Tim
Regulatory T (Treg) cells characterized by the transcription factor FoxP3 have a fundamental role in the establishment and maintenance of peripheral tolerance, and have transcriptional and functional
Background: Xianyang city is one of the main epidemic areas of Hemorrhagic fever with renal syndrome (HFRS) in the northwest of China.Although the HFRS vaccination program was provided freely, the imp
The emergence of severe cases of human influenza A (H7N9) viral infection in China in the spring of 2003 resulted in a global effort to rapidly develop an effective candidate vaccine.
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine produced by several cells.It can induce the differentiation and maturation of myeloid dendritic cells (DCs) to improve the funct
Objective: we have investigated the cellular and humoral immune responses in ex vivo and immune protection in vivo of immunized mice by DNA vaccine encoding TXR1.