Traditional Chinese Medicines (TCMs) have played an important role in Asia as major clinical therapies for thousands of years.In the past decade, the usage of TCMs has expanded globally and gained increasing acceptance as a complement to modern Western medicine.A large number of TCMs are chiral compounds.Since optical isomers could possess considerable different bioactivities, it is therefore important to quantify enantiomers in order to better understand stereo-specific bio-disposition of these enantiomers in TCM.