Regulation of epithelial Na+ channel (ENaC) trafficking by aldosterone

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户:regelus
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Na+ reabsorption in renal collecting ducts is one of the key factors regulating extracellular fluid volume and blood pressure.The rate-limiting step in transepithelial Na+ reabsorption in principal cells of renal collecting duct is the apical entry step mediated by epithelial Na+ channels (ENaC).Aldosterone is well known to elevate ENaC synthesis.
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