【摘 要】
：
Objective:As an important cooperated immune response of innate and adaptive immunity,CD56+ NK cell-mediated antibody-dependent cellular cytotoxicity(NK-ADCC)is of considerable interest in viral infect
【机 构】
：
Department of Microbiology and Infectious Disease Center,Peking University Health Science Center,Bei
【出 处】
：
第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会
论文部分内容阅读
Objective:As an important cooperated immune response of innate and adaptive immunity,CD56+ NK cell-mediated antibody-dependent cellular cytotoxicity(NK-ADCC)is of considerable interest in viral infection.However,limited knowledge was known about NK-ADCC responses in chronic HCV infection.
其他文献
Recent studies have identified a number of HIV restriction factors.Thus,we examined the expression of several key antiviral cellular factors(OAS-1,MxA,A3G,PKR and Tetherin)in PBMCs from HIV-infected p
The hepatitis B virus (HBV) remains to be a global health threat since the chronic HBV infection may lead to liver cirrhosis or cancer.Current antiviral therapies with nucleoside analogues can inhibit
Proviral regions have been identified in the genomes of many haloarchaea,but only a few archaeal halophilic temperate viruses have been studied.During the study on icosahedral membrane-containing halo
The order Herpesvirales,as the newest taxonomy summarizing herpesviruses,consists of the families Herpesviridae,Alloherpesviridae,and Malacoherpesviridae.The family Herpesviridae contains three subfam
Marine viruses that infect phytoplankton are recognized as a major ecological and evolutionary driving force,shaping community structure and nutrient cycling in the marine environment.Coccolithophores
目的：分析慢性乙型肝炎(CHB)患者外周血中T细胞亚群表面程序性死亡受体1(PD-1)表达的变化特点.方法：采用流式细胞仪回顾性分析10例慢性乙型肝炎患者及10例健康对照者外周血中T细胞及其亚群CD4-CD8-T细胞、CD4+CD8-T细胞、CD4-CD8+T细胞、CD4+CD8+T、CD4+CD8+细胞表面PD-1的表达水平.结果：与健康对照组相比,CHB患者组T细胞及其主要亚群CD4-CD8-
Virus labeling is essential for getting knowledge of virus-cell interactions.Quantum dots (QDs),as a photochemical stable nanomaterial,make long-time tracking possible.According to the fact that virus
家蚕核型多角体病毒(Bombyx mori nucleopolyhedrovirus,BmNPV)是能够自身编码泛素基因的杆状病毒属病毒成员,而泛素-蛋白酶体系统在BmNPV的早期复制过程中扮演了重要角色,所以在BmNPV侵染过程中,病毒及宿主泛素化蛋白的鉴定对于研究泛素-蛋白酶体系统在病毒复制中所起得作用显得尤为重要。本研究借助Red重组和杆状病毒表达系统构建出只融合表达泛素-myc-his蛋白
Purpose:To investigate the potential use of CRISPR/Cas9 approach for eradicatinghepatitis B virus(HBV)infection,we designed and screened for the most effective gRNAs against HBV of genotypes A-D,and d
Purpose:To investigate the changes of NK profile in peripheral blood after surgery and tumor tissues of hepatocellular carcinoma(HCC)patients,as well as the underlying reason.Experimental Design: Peri