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  5. Prosaposin facilitates lysosomal delivery of progranulin,a frontotemporal lobar degeneration and neu

Prosaposin facilitates lysosomal delivery of progranulin,a frontotemporal lobar degeneration and neu

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：shinmagi
【摘 要】
：
Mutations in the progranulin(PGRN)gene have been linked to two distinct neurodegenerative diseases,frontotemporal lobar degeneration(FTLD)and neuronal ceroid lipofuscinosis(NCL).
【作 者】
：
Xiaolai Zhou Lirong Sun Francisco Bastos de Oliveira Xiaoyang Qi William J.Brown Marcus Smolka Ying Sun Fenghua Hu 
【机 构】
：
Department of Molecular Biology and Genetics,Cornell University,Ithaca,NY USA;Weill Institute for Ce
【出 处】
：
The 6th FAONS Congress and 11th Biennial Conference of CNS(第
【发表日期】
：
2015年3期
【关键词】
：
progranulin (PGRN) prosaposin (PSAP) frontotemporal lobar degeneration (FTLD) ne 
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　　Mutations in the progranulin(PGRN)gene have been linked to two distinct neurodegenerative diseases,frontotemporal lobar degeneration(FTLD)and neuronal ceroid lipofuscinosis(NCL).
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