Robust modeling of RNA sequencing data

来源 :上海交通大学 | 被引量 : 0次 | 上传用户:sssmickey
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  High-throughput sequencing of transcriptomes(RNA-Seq)is a widely used approach for measuring gene expression.However,systematic biases as well as incomplete transcript annotation databases may lead to unreliable transcript abundance estimates.
其他文献
Logit models are popular tools for analyzing discrete choice and ranking data.The models assume that judges rate each item with a measurable utility,and the ordering of a judges utilities determines t
Benjamini and Yekutieli(2005)introduced the concept of the false coverage-statement rate(FCR)to account for selection when the confidence intervals are constructed only for the selected parameters.Dos
Recent advances in genomic and proteomic technologies have stimulated a large number of molecular biomarker discovery studies of various diseases.To date,the number and the quality of the technical re
Partially observed cured data occur in the analysis of spontaneous abortion(SAB)in observational studies in pregnancy.In contrast to the traditional cured data,such data has a observable cured portion
In many clinical trials studying neurodegenerative diseases such as Parkinsons disease(PD),multiple longitudinal outcomes are collected to fully explore the multidimensional impairment caused by this
Epistasis plays a critical rule in understanding the regulation mechanisms and is an es-sential component of the genetic architecture of the gene expressions.However,interaction analysis of gene expre
会议
会议
The sufficient dimension reduction(SDR)is a successive tool for reducing the dimensionality of predictors by finding the central subspace,a minimal subspace of predictors that preserves all the regres
Two-phase optional randomized response(TORR)technique has been proposed.The proposed randomized response performs much better in general than the existing randomized response techniques.Theoretical an