The spirostanol saponin RCE-4 from Reineckia carnea inducing Caski cell apoptosis via inhibiting PI3

来源 :2015中国植物学会第十三届全国药用植物及植物药学术研讨会暨2015年海峡两岸中医药科学交流会 | 被引量 : 0次 | 上传用户:liongliong582
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  Cervical cancer is the second leading cause of cancer deaths in women worldwide and remains a leading cause of mortality among women of reproductive age.It is reported that there are approximately 530,000 new cases and 275,000 deaths occurring each year, and most of these cases take place in the developing countries, relatively young women and occur at the advanced stage.It is generally accepted that radical surgery or radiotherapy can be curative for the majority of patients with early-stage cervical cancer, while chemotherapy or neoadjuvant chemotherapy is always the first choice for those patients with advanced cervical cancer, where the prognosis remains very poor.
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