【摘 要】
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Calcium binding proteins are well known to be expressed by different groups of hippocampal interneurons; however,whether voltage-dependent calcium channels
【机 构】
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Department of Anatomy and Histology, School of Medicine, Xi'an Jiaotong University, Xi'an 710061,
【出 处】
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中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the
论文部分内容阅读
Calcium binding proteins are well known to be expressed by different groups of hippocampal interneurons; however,whether voltage-dependent calcium channels (Cav) are also localized in these neurons,changed during and after status epilepticus (SE),and involved in epileptic activity have not been reported.In the present study,we showed the colocalization of three subtypes of voltage-gated calcium channels (Cav1.2,Cav1.3,or Cav2.1) with different calcium binding proteins such as calbindin (CB),calretinin (CR),and parvalbumin (PV).At early stages during and after pilocarpine-induced status epilepticus (PISE),significant changes of expression of Cav 1.2,Cav 1.3 (L-type),and Cav2.1 (P/Q-type) were found in different groups of hippocampal neurons.
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