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Objective To evaluate the efficacy of multimodal-antiemetic therapy on postoperative nausea and vomiting (PONV)in patients undergoing gynecological.laparoscopy.Methods 129 patients scheduled for gynecological laparoscopy were randomly allocated to multimodal-antiemetic group (group M, with 65 cases) or ondansetron control group (group C, with 64 cases).