Rechallenge with gefitinib after severe drug-induced hepatotoxicity in a patient with advanced non-s

来源 :第十六届全国临床肿瘤学大会暨2013年CSCO学术年会 | 被引量 : 0次 | 上传用户:yanwang114
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目的: Gefitinib has come to be the most widely used epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) in treatment of advanced non-small cell lung cancer (NSCLC) in Asian patients.Common side effects of gefitinib consist of mild to moderate skin rash and diarrhea, however, drug-induced liver injury of various severities is underappreciated in long-term administered patients and rarely reported.
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