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5. Fabrication of the supramolecular complexes of matrine by host-guest binding and electrostatic inter

Fabrication of the supramolecular complexes of matrine by host-guest binding and electrostatic inter

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：wra207

【摘 要】

：

Matrine (MAT) is widely used in the treatment of ulcerative colitis[1].However,it cannot reach an effective concentration in the colorectal area,leading to low availability and severe toxic side-effec

【作 者】

：

Huimin Chu Yajuan Wang Zhizhong Wang Qing Huang 

【机 构】

：

Department of Pharmacy,Ningxia Medical University,Yinchuan 750004,China

【出 处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

sulfobutyl ether β-cyclodextrin matrine electrostatic interaction controlled del 

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　　Matrine (MAT) is widely used in the treatment of ulcerative colitis[1].However,it cannot reach an effective concentration in the colorectal area,leading to low availability and severe toxic side-effects of upper gastrointestinal tract in large doses.

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