【摘 要】
：
Apoptosis of bone marrow-derived mesenchymal stem cells (BMMSCs) is an essential pathogenic factor of osteoporosis.Ginsenoside-Rb2 (Rb2),a 20(S)-protopanaxadiol glycoside extracted from ginseng,is a p
【机 构】
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Xijing Hospital of The Fourth Military Medical University
【出 处】
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中华医学会第八次全国骨质疏松和骨矿盐疾病学术会议
论文部分内容阅读
Apoptosis of bone marrow-derived mesenchymal stem cells (BMMSCs) is an essential pathogenic factor of osteoporosis.Ginsenoside-Rb2 (Rb2),a 20(S)-protopanaxadiol glycoside extracted from ginseng,is a potent treatment for bone loss,which raises interest regarding the bone metabolism area.In the present study,we found that dose-response Rb2 inhibited high dosage of dexamethasone (Dex)-induced apoptosis in primary murine BMMSCs.Interestingly,Rb2 promoted GPR120 induction,which is the unsaturated long-chain fatty acid receptor.
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