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5. Chemically-Defined Natural N-Glycan Scaffold Efficiently Delivers Toxins to B-Lymphoma Cells

Chemically-Defined Natural N-Glycan Scaffold Efficiently Delivers Toxins to B-Lymphoma Cells

来源 :第二届糖合成化学青年学术研讨会 | 被引量 : 0次 | 上传用户：kayak6789

【摘 要】

：

CD22 is a sialic acid-binding immunoglobulin-like lectin(Siglec) that is highly expressed on B-cell lymphomas,and is a validated target for antibody and nanopar

【作 者】

：

Wenjie Peng James C Paulson 

【机 构】

：

DepartmentsofMolecularMedicineandDepartmentofImmunology&MicrobiologyTheScrippsResearchInstitute,LaJo

【出 处】

：

第二届糖合成化学青年学术研讨会

【发表日期】

：

2017年5期

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论文部分内容阅读

CD22 is a sialic acid-binding immunoglobulin-like lectin(Siglec) that is highly expressed on B-cell lymphomas,and is a validated target for antibody and nanoparticle based therapeutics;However,such cell targeted therapeutics are limited by their complexity,heterogeneity and difficulties in producing.

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