Objective: Alzheimers disease(AD)is a neurodegenerative disease.The two obvious neuropatholopgical changes in AD are senile plaques(SP)and neurofibrillary tangles(NFT).
Early,reliable and non-invasive diagnosis of Alzheimer disease(AD)is a great challenge,which makes the prognosis and therapeutic interventions quite difficult.
Parkinsons disease(PD)is a progressive neurodegenerative movement disorder that is caused predominantly by the degeneration of the nigrostriatal dopaminergic pathway.
Objective Bisphosphonates(BP)is a category of drugs that are used to treat various bone diseases,such as osteoporosis,Pagets disease,bone malignancy and other skeletal complications involving excessiv
Parkinsons disease(PD)is characterized by degeneration of dopaminergic neurons in the substantia nigra.Besides,the changes of dopaminergic neurons have been reported in enteric nervous system of PD pa
Objective Parkinson disease(PD)is a chronic progressive disease which could involve multiple systems at its early stage while the central nervous system was finally injured at its later stage and mani