【摘 要】
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Neural tube defects (NTD) and congenital heart disease (CHD) are the top two birth defects in China and among the world.Genetic factors play an important role in the progression of these diseases as m
【机 构】
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State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contem
【出 处】
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2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议
论文部分内容阅读
Neural tube defects (NTD) and congenital heart disease (CHD) are the top two birth defects in China and among the world.Genetic factors play an important role in the progression of these diseases as more than 70％ NTD can be attributed to genetic factors.Identifying more causative genes and further understanding the genetic mechanism behind those birth defects can help to establish a prenatal genetic screening list, which is a key step in reducing the incidence of NTD and CHD.However, it is very hard to find relative pedigree due to the severity of those diseases.
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