【摘 要】
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In daily life,SO32-/HSO3-have been extensively used as an antimicrobial agent,an enzyme inhibitor and an antioxidant for foods products,beverages and pharmaceutical products.However,numerous epidemiol
【机 构】
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Institute of Molecular Science, Key Laboratory of Materials for Energy Conversion and Storage of Sha
【出 处】
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中国化学会第十三届全国有机合成化学学术研讨会
论文部分内容阅读
In daily life,SO32-/HSO3-have been extensively used as an antimicrobial agent,an enzyme inhibitor and an antioxidant for foods products,beverages and pharmaceutical products.However,numerous epidemiological studies have confirmed that the intake of an excess amount of these anions would induce harmful effects to cells and tissues in some individuals.Consequently,a novel highly sensitive and selectiveturn-onfluorescent probe for detecting sulfite has been developed by an nucleophilic addition mechanism through a rational design.It displays a 33-fold fluorescence intensity enhancement.More importantly,the probe features a rapid signal response time (within 4 min),a good linearity range and the detection limit is as low as 8.8 nM.In addition,the ability of the probe to detect sulfite in living cells (A549 cells) via an enhancement of the fluorescence has also been proved.
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